AMD Instinct MI300X VS AMD Instinct MI325X

Both the Instinct MI300X and Instinct MI325X are built on AMD's CDNA 3 architecture. This comparison helps you choose between different configurations within the same GPU family.

AMD

Instinct MI300X

VRAM 192GB
FP32 163.4 TFLOPS
TDP 750W
From $1.99/h 6 providers
AMD

Instinct MI325X

VRAM 256GB
FP32 163 TFLOPS
TDP 750W
From $2.29/h 3 providers

📊 Detailed Specifications Comparison

Specification Instinct MI300X Instinct MI325X Difference
Architecture & Design
Architecture CDNA 3 CDNA 3 -
Process Node 5nm + 6nm 5nm -
Target Market datacenter datacenter -
Form Factor OAM OAM -
Memory
VRAM Capacity 192GB 256GB -25%
Memory Type HBM3 HBM3e -
Memory Bandwidth 5.3 TB/s 6.0 TB/s -12%
Memory Bus 8192-bit 8192-bit -
Compute Units
Stream Processors 19,456 19,456 -
Performance (TFLOPS)
FP32 (Single Precision) 163.4 TFLOPS 163 TFLOPS
FP16 (Half Precision) 1307.4 TFLOPS 2600 TFLOPS -50%
FP64 (Double Precision) 81.7 TFLOPS N/A
Power & Connectivity
TDP (Power) 750W 750W
PCIe PCIe 5.0 x16 PCIe 5.0 x16 -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

AMD Instinct MI325X

Higher VRAM capacity and memory bandwidth are critical for training large language models. The Instinct MI325X offers 256GB compared to 192GB.

AI Inference

AMD Instinct MI325X

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

AMD Instinct MI300X

Based on current cloud pricing, the Instinct MI300X starts at a lower hourly rate.

AMD Instinct MI300X is Best For:

  • LLM inference at scale
  • Large VRAM capacity
  • CUDA-only software

AMD Instinct MI325X is Best For:

  • AI training
  • Large model inference
  • CUDA-only software

Frequently Asked Questions

Which GPU is better for AI training: Instinct MI300X or Instinct MI325X?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The Instinct MI300X offers 192GB of HBM3 memory with 5.3 TB/s bandwidth, while the Instinct MI325X provides 256GB of HBM3e with 6.0 TB/s bandwidth. For larger models, the Instinct MI325X's higher VRAM capacity gives it an advantage.

What is the price difference between Instinct MI300X and Instinct MI325X in the cloud?

Cloud GPU rental prices vary by provider and region. Based on our data, Instinct MI300X starts at $1.99/hour while Instinct MI325X starts at $2.29/hour. This represents a 13% price difference.

Can I use Instinct MI325X instead of Instinct MI300X for my workload?

It depends on your specific requirements. If your model fits within 256GB of VRAM and you don't need the additional throughput of the Instinct MI300X, the Instinct MI325X can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the Instinct MI300X's architecture may be essential.

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