NVIDIA A100 40GB VS AMD Instinct MI355X

Choosing between **A100 40GB** and **Instinct MI355X** depends on your specific AI workload requirements. The **Instinct MI355X** leads in both memory capacity and raw compute power, making it a stronger choice for high-end LLM training. Currently, you can rent these GPUs starting from **$0.00/h** and **$2.29/h** respectively across 2 providers.

NVIDIA

A100 40GB

VRAM 40GB
FP32 19.5 TFLOPS
TDP 250W
From $0.89/h Estimated Price
AMD

Instinct MI355X

VRAM 288GB
FP32 210 TFLOPS
TDP 1000W
From $2.29/h 2 providers

📊 Detailed Specifications Comparison

Specification A100 40GB Instinct MI355X Difference
Architecture & Design
Architecture Ampere CDNA 4 -
Process Node 7nm 3nm -
Target Market datacenter datacenter -
Form Factor SXM4 / PCIe OAM -
Memory & Bandwidth
VRAM Capacity 40GB 288GB -86%
Memory Type HBM2 HBM3e -
Memory Bandwidth 1.5 TB/s 8.0 TB/s -81%
Memory Bus Width 5120-bit 8192-bit -
Compute Infrastructure
CUDA Cores 6,912 N/A
Tensor Cores (AI) 432 N/A
Stream Processors N/A 24,576
AI & Compute Performance (TFLOPS)
FP32 (Single Precision) 19.5 TFLOPS 210 TFLOPS -91%
FP16 (Half Precision) 312 TFLOPS N/A
Power & Efficiency
TDP (Thermal Design Power) 250W 1000W -75%
PCIe Interface PCIe 4.0 x16 PCIe 5.0 x16 -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

AMD Instinct MI355X

Higher VRAM capacity and memory bandwidth are critical for training large language models. The Instinct MI355X offers 288GB compared to 40GB.

AI Inference

NVIDIA A100 40GB

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

AMD Instinct MI355X

Compare live pricing to find the best value for your specific workload.

Automated Comparison

Technical Deep Dive: A100 40GB vs Instinct MI355X

This head-to-head pits NVIDIA's Ampere against AMD's CDNA 4. The Instinct MI355X has a significant **248GB VRAM advantage**, which is crucial for training massive datasets or large language models.

NVIDIA A100 40GB is Best For:

  • Mainstream AI training
  • Scientific computing
  • Memory-intensive LLM training

AMD Instinct MI355X is Best For:

  • Massive LLM training
  • Budget projects

Frequently Asked Questions

Which GPU is better for AI training: A100 40GB or Instinct MI355X?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The A100 40GB offers 40GB of HBM2 memory with 1.5 TB/s bandwidth, while the Instinct MI355X provides 288GB of HBM3e with 8.0 TB/s bandwidth. For larger models, the Instinct MI355X's higher VRAM capacity gives it an advantage.

What is the price difference between A100 40GB and Instinct MI355X in the cloud?

Cloud GPU rental prices vary by provider and region. Check our price tracker for the latest rates from 50+ cloud providers.

Can I use Instinct MI355X instead of A100 40GB for my workload?

It depends on your specific requirements. If your model fits within 288GB of VRAM and you don't need the additional throughput of the A100 40GB, the Instinct MI355X can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the A100 40GB's architecture may be essential.

Ready to rent a GPU?

Compare live pricing across 50+ cloud providers and find the best deal.