NVIDIA A100 80GB VS AMD Instinct MI325X

Choosing between **A100 80GB** and **Instinct MI325X** depends on your specific AI workload requirements. The **Instinct MI325X** leads in both memory capacity and raw compute power, making it a stronger choice for high-end LLM training. Currently, you can rent these GPUs starting from **$0.40/h** and **$1.69/h** respectively across 44 providers.

NVIDIA

A100 80GB

VRAM 80GB
FP32 19.5 TFLOPS
TDP 400W
From $0.40/h 41 providers
AMD

Instinct MI325X

VRAM 256GB
FP32 163 TFLOPS
TDP 750W
From $1.69/h 3 providers

📊 Detailed Specifications Comparison

Specification A100 80GB Instinct MI325X Difference
Architecture & Design
Architecture Ampere CDNA 3 -
Process Node 7nm 5nm -
Target Market datacenter datacenter -
Form Factor SXM4 / PCIe OAM -
Memory & Bandwidth
VRAM Capacity 80GB 256GB -69%
Memory Type HBM2e HBM3e -
Memory Bandwidth 2.0 TB/s 6.0 TB/s -66%
Memory Bus Width 5120-bit 8192-bit -
Compute Infrastructure
CUDA Cores 6,912 N/A
Tensor Cores (AI) 432 N/A
Stream Processors N/A 19,456
AI & Compute Performance (TFLOPS)
FP32 (Single Precision) 19.5 TFLOPS 163 TFLOPS -88%
FP16 (Half Precision) 312 TFLOPS 2,600 TFLOPS -88%
TF32 (Tensor Float) 156 TFLOPS N/A
FP64 (Double Precision) 9.7 TFLOPS N/A
INT8 (Integer Precision) 624 TOPS N/A
Power & Efficiency
TDP (Thermal Design Power) 400W 750W -47%
PCIe Interface PCIe 4.0 x16 PCIe 5.0 x16 -
Multi-GPU Interconnect NVLink 3.0 (600 GB/s) None -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

AMD Instinct MI325X

Higher VRAM capacity and memory bandwidth are critical for training large language models. The Instinct MI325X offers 256GB compared to 80GB.

AI Inference

AMD Instinct MI325X

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

NVIDIA A100 80GB

Based on current cloud pricing, the A100 80GB starts at a lower hourly rate.

Automated Comparison

Technical Deep Dive: A100 80GB vs Instinct MI325X

This head-to-head pits NVIDIA's Ampere against AMD's CDNA 3. The Instinct MI325X has a significant **176GB VRAM advantage**, which is crucial for training massive datasets or large language models. From a cost perspective, the **A100 80GB** is currently about **76% cheaper** per hour, offering better value for budget-conscious projects.

NVIDIA A100 80GB is Best For:

  • AI model training
  • Scientific computing
  • Newest FP8 precision workloads

AMD Instinct MI325X is Best For:

  • AI training
  • Large model inference
  • CUDA-only software

Frequently Asked Questions

Which GPU is better for AI training: A100 80GB or Instinct MI325X?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The A100 80GB offers 80GB of HBM2e memory with 2.0 TB/s bandwidth, while the Instinct MI325X provides 256GB of HBM3e with 6.0 TB/s bandwidth. For larger models, the Instinct MI325X's higher VRAM capacity gives it an advantage.

What is the price difference between A100 80GB and Instinct MI325X in the cloud?

Cloud GPU rental prices vary by provider and region. Based on our data, A100 80GB starts at $0.40/hour while Instinct MI325X starts at $1.69/hour. This represents a 76% price difference.

Can I use Instinct MI325X instead of A100 80GB for my workload?

It depends on your specific requirements. If your model fits within 256GB of VRAM and you don't need the additional throughput of the A100 80GB, the Instinct MI325X can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the A100 80GB's NVLink support (NVLink 3.0 (600 GB/s)) may be essential.

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