NVIDIA A800 80GB VS AMD Instinct MI250

Choosing between **A800** and **Instinct MI250** depends on your specific AI workload requirements. The **Instinct MI250** leads in both memory capacity and raw compute power, making it a stronger choice for high-end LLM training. Currently, you can rent these GPUs starting from **$0.80/h** and **$1.30/h** respectively across 4 providers.

NVIDIA

A800

VRAM 80GB
FP32 19.5 TFLOPS
TDP 400W
From $0.80/h 3 providers
AMD

Instinct MI250

VRAM 128GB
FP32 45.3 TFLOPS
TDP 500W
From $1.30/h 1 providers

📊 Detailed Specifications Comparison

Specification A800 Instinct MI250 Difference
Architecture & Design
Architecture Ampere CDNA 2 -
Process Node 7nm 6nm -
Target Market datacenter datacenter -
Form Factor SXM4 / PCIe OAM -
Memory & Bandwidth
VRAM Capacity 80GB 128GB -38%
Memory Type HBM2e HBM2e -
Memory Bandwidth 2.0 TB/s 3.2 TB/s -40%
Memory Bus Width 5120-bit 8192-bit -
Compute Infrastructure
CUDA Cores 6,912 N/A
Tensor Cores (AI) 432 N/A
Stream Processors N/A 13,312
AI & Compute Performance (TFLOPS)
FP32 (Single Precision) 19.5 TFLOPS 45.3 TFLOPS -57%
FP16 (Half Precision) 312 TFLOPS N/A
FP64 (Double Precision) N/A 45.3 TFLOPS
Power & Efficiency
TDP (Thermal Design Power) 400W 500W -20%
PCIe Interface PCIe 4.0 x16 PCIe 4.0 x16 -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

NVIDIA A800 80GB

Higher VRAM capacity and memory bandwidth are critical for training large language models. The Instinct MI250 offers 128GB compared to 80GB.

AI Inference

NVIDIA A800 80GB

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

NVIDIA A800 80GB

Based on current cloud pricing, the A800 starts at a lower hourly rate.

Automated Comparison

Technical Deep Dive: A800 vs Instinct MI250

This head-to-head pits NVIDIA's Ampere against AMD's CDNA 2. The Instinct MI250 has a significant **48GB VRAM advantage**, which is crucial for training massive datasets or large language models. From a cost perspective, the **A800** is currently about **38% cheaper** per hour, offering better value for budget-conscious projects.

NVIDIA A800 80GB is Best For:

  • AI training
  • Scientific computing
  • International high-bandwidth needs

AMD Instinct MI250 is Best For:

  • HPC
  • Matrix math workloads
  • CUDA native apps

Frequently Asked Questions

Which GPU is better for AI training: A800 or Instinct MI250?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The A800 offers 80GB of HBM2e memory with 2.0 TB/s bandwidth, while the Instinct MI250 provides 128GB of HBM2e with 3.2 TB/s bandwidth. For larger models, the Instinct MI250's higher VRAM capacity gives it an advantage.

What is the price difference between A800 and Instinct MI250 in the cloud?

Cloud GPU rental prices vary by provider and region. Based on our data, A800 starts at $0.80/hour while Instinct MI250 starts at $1.30/hour. This represents a 38% price difference.

Can I use Instinct MI250 instead of A800 for my workload?

It depends on your specific requirements. If your model fits within 128GB of VRAM and you don't need the additional throughput of the A800, the Instinct MI250 can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the A800's architecture may be essential.

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