NVIDIA B100 VS AMD Instinct MI250

Choosing between **B100** and **Instinct MI250** depends on your specific AI workload requirements. The **B100** leads in both memory capacity and raw compute power, making it a stronger choice for high-end LLM training. Currently, you can rent these GPUs starting from **$0.00/h** and **$1.30/h** respectively across 1 providers.

NVIDIA

B100

VRAM 192GB
FP32 70 TFLOPS
TDP 700W
From $2.50/h Estimated Price
AMD

Instinct MI250

VRAM 128GB
FP32 45.3 TFLOPS
TDP 500W
From $1.30/h 1 providers

📊 Detailed Specifications Comparison

Specification B100 Instinct MI250 Difference
Architecture & Design
Architecture Blackwell CDNA 2 -
Process Node 4nm 6nm -
Target Market datacenter datacenter -
Form Factor SXM OAM -
Memory & Bandwidth
VRAM Capacity 192GB 128GB +50%
Memory Type HBM3e HBM2e -
Memory Bandwidth 8.0 TB/s 3.2 TB/s +150%
Memory Bus Width 8192-bit 8192-bit -
Compute Infrastructure
CUDA Cores 14,336 N/A
Tensor Cores (AI) 448 N/A
Stream Processors N/A 13,312
AI & Compute Performance (TFLOPS)
FP32 (Single Precision) 70 TFLOPS 45.3 TFLOPS +55%
FP16 (Half Precision) 3,500 TFLOPS N/A
TF32 (Tensor Float) 1,750 TFLOPS N/A
FP64 (Double Precision) 35 TFLOPS 45.3 TFLOPS -23%
INT8 (Integer Precision) 7,000 TOPS N/A
Power & Efficiency
TDP (Thermal Design Power) 700W 500W +40%
PCIe Interface PCIe 5.0 x16 PCIe 4.0 x16 -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

NVIDIA B100

Higher VRAM capacity and memory bandwidth are critical for training large language models. The B100 offers 192GB compared to 128GB.

AI Inference

NVIDIA B100

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

AMD Instinct MI250

Compare live pricing to find the best value for your specific workload.

Automated Comparison

Technical Deep Dive: B100 vs Instinct MI250

This head-to-head pits NVIDIA's Blackwell against AMD's CDNA 2. The B100 has a significant **64GB VRAM advantage**, which is crucial for training massive datasets or large language models.

NVIDIA B100 is Best For:

  • Large-scale AI training
  • Budget deployments

AMD Instinct MI250 is Best For:

  • HPC
  • Matrix math workloads
  • CUDA native apps

Frequently Asked Questions

Which GPU is better for AI training: B100 or Instinct MI250?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The B100 offers 192GB of HBM3e memory with 8.0 TB/s bandwidth, while the Instinct MI250 provides 128GB of HBM2e with 3.2 TB/s bandwidth. For larger models, the B100's higher VRAM capacity gives it an advantage.

What is the price difference between B100 and Instinct MI250 in the cloud?

Cloud GPU rental prices vary by provider and region. Check our price tracker for the latest rates from 50+ cloud providers.

Can I use Instinct MI250 instead of B100 for my workload?

It depends on your specific requirements. If your model fits within 128GB of VRAM and you don't need the additional throughput of the B100, the Instinct MI250 can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the B100's architecture may be essential.

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