NVIDIA B100 VS AMD Instinct MI325X

Choosing between **B100** and **Instinct MI325X** depends on your specific AI workload requirements. The **Instinct MI325X** leads in both memory capacity and raw compute power, making it a stronger choice for high-end LLM training. Currently, you can rent these GPUs starting from **$0.00/h** and **$1.69/h** respectively across 3 providers.

NVIDIA

B100

VRAM 192GB
FP32 70 TFLOPS
TDP 700W
From $2.50/h Estimated Price
AMD

Instinct MI325X

VRAM 256GB
FP32 163 TFLOPS
TDP 750W
From $1.69/h 3 providers

📊 Detailed Specifications Comparison

Specification B100 Instinct MI325X Difference
Architecture & Design
Architecture Blackwell CDNA 3 -
Process Node 4nm 5nm -
Target Market datacenter datacenter -
Form Factor SXM OAM -
Memory & Bandwidth
VRAM Capacity 192GB 256GB -25%
Memory Type HBM3e HBM3e -
Memory Bandwidth 8.0 TB/s 6.0 TB/s +33%
Memory Bus Width 8192-bit 8192-bit -
Compute Infrastructure
CUDA Cores 14,336 N/A
Tensor Cores (AI) 448 N/A
Stream Processors N/A 19,456
AI & Compute Performance (TFLOPS)
FP32 (Single Precision) 70 TFLOPS 163 TFLOPS -57%
FP16 (Half Precision) 3,500 TFLOPS 2,600 TFLOPS +35%
TF32 (Tensor Float) 1,750 TFLOPS N/A
FP64 (Double Precision) 35 TFLOPS N/A
INT8 (Integer Precision) 7,000 TOPS N/A
Power & Efficiency
TDP (Thermal Design Power) 700W 750W -7%
PCIe Interface PCIe 5.0 x16 PCIe 5.0 x16 -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

NVIDIA B100

Higher VRAM capacity and memory bandwidth are critical for training large language models. The Instinct MI325X offers 256GB compared to 192GB.

AI Inference

NVIDIA B100

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

AMD Instinct MI325X

Compare live pricing to find the best value for your specific workload.

Automated Comparison

Technical Deep Dive: B100 vs Instinct MI325X

This head-to-head pits NVIDIA's Blackwell against AMD's CDNA 3. The Instinct MI325X has a significant **64GB VRAM advantage**, which is crucial for training massive datasets or large language models.

NVIDIA B100 is Best For:

  • Large-scale AI training
  • Budget deployments

AMD Instinct MI325X is Best For:

  • AI training
  • Large model inference
  • CUDA-only software

Frequently Asked Questions

Which GPU is better for AI training: B100 or Instinct MI325X?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The B100 offers 192GB of HBM3e memory with 8.0 TB/s bandwidth, while the Instinct MI325X provides 256GB of HBM3e with 6.0 TB/s bandwidth. For larger models, the Instinct MI325X's higher VRAM capacity gives it an advantage.

What is the price difference between B100 and Instinct MI325X in the cloud?

Cloud GPU rental prices vary by provider and region. Check our price tracker for the latest rates from 50+ cloud providers.

Can I use Instinct MI325X instead of B100 for my workload?

It depends on your specific requirements. If your model fits within 256GB of VRAM and you don't need the additional throughput of the B100, the Instinct MI325X can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the B100's architecture may be essential.

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