NVIDIA B200 VS AMD Instinct MI250

Choosing between **B200** and **Instinct MI250** depends on your specific AI workload requirements. The **B200** leads in both memory capacity and raw compute power, making it a stronger choice for high-end LLM training. Currently, you can rent these GPUs starting from **$2.25/h** and **$1.30/h** respectively across 21 providers.

NVIDIA

B200

VRAM 192GB
FP32 90 TFLOPS
TDP 1000W
From $2.25/h 20 providers
AMD

Instinct MI250

VRAM 128GB
FP32 45.3 TFLOPS
TDP 500W
From $1.30/h 1 providers

📊 Detailed Specifications Comparison

Specification B200 Instinct MI250 Difference
Architecture & Design
Architecture Blackwell CDNA 2 -
Process Node 4nm 6nm -
Target Market datacenter datacenter -
Form Factor SXM OAM -
Memory & Bandwidth
VRAM Capacity 192GB 128GB +50%
Memory Type HBM3e HBM2e -
Memory Bandwidth 8.0 TB/s 3.2 TB/s +150%
Memory Bus Width 8192-bit 8192-bit -
Compute Infrastructure
CUDA Cores 18,432 N/A
Tensor Cores (AI) 576 N/A
Stream Processors N/A 13,312
AI & Compute Performance (TFLOPS)
FP32 (Single Precision) 90 TFLOPS 45.3 TFLOPS +99%
FP16 (Half Precision) 4,500 TFLOPS N/A
TF32 (Tensor Float) 2,250 TFLOPS N/A
FP64 (Double Precision) 45 TFLOPS 45.3 TFLOPS
INT8 (Integer Precision) 9,000 TOPS N/A
Power & Efficiency
TDP (Thermal Design Power) 1000W 500W +100%
PCIe Interface PCIe 5.0 x16 PCIe 4.0 x16 -
Multi-GPU Interconnect NVLink 5.0 (1.8 TB/s) None -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

NVIDIA B200

Higher VRAM capacity and memory bandwidth are critical for training large language models. The B200 offers 192GB compared to 128GB.

AI Inference

NVIDIA B200

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

AMD Instinct MI250

Based on current cloud pricing, the Instinct MI250 starts at a lower hourly rate.

Automated Comparison

Technical Deep Dive: B200 vs Instinct MI250

This head-to-head pits NVIDIA's Blackwell against AMD's CDNA 2. The B200 has a significant **64GB VRAM advantage**, which is crucial for training massive datasets or large language models. From a cost perspective, the **Instinct MI250** is currently about **42% cheaper** per hour, offering better value for budget-conscious projects.

NVIDIA B200 is Best For:

  • Next-gen LLM training
  • Trillion parameter models
  • Cost-sensitive projects

AMD Instinct MI250 is Best For:

  • HPC
  • Matrix math workloads
  • CUDA native apps

Frequently Asked Questions

Which GPU is better for AI training: B200 or Instinct MI250?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The B200 offers 192GB of HBM3e memory with 8.0 TB/s bandwidth, while the Instinct MI250 provides 128GB of HBM2e with 3.2 TB/s bandwidth. For larger models, the B200's higher VRAM capacity gives it an advantage.

What is the price difference between B200 and Instinct MI250 in the cloud?

Cloud GPU rental prices vary by provider and region. Based on our data, B200 starts at $2.25/hour while Instinct MI250 starts at $1.30/hour. This represents a 73% price difference.

Can I use Instinct MI250 instead of B200 for my workload?

It depends on your specific requirements. If your model fits within 128GB of VRAM and you don't need the additional throughput of the B200, the Instinct MI250 can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the B200's NVLink support (NVLink 5.0 (1.8 TB/s)) may be essential.

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