NVIDIA GH200 Grace Hopper VS AMD Instinct MI325X

Choosing between **GH200** and **Instinct MI325X** depends on your specific AI workload requirements. The **Instinct MI325X** leads in both memory capacity and raw compute power, making it a stronger choice for high-end LLM training. Currently, you can rent these GPUs starting from **$1.49/h** and **$1.69/h** respectively across 7 providers.

NVIDIA

GH200

VRAM 96GB
FP32 67 TFLOPS
TDP 900W
From $1.49/h 4 providers
AMD

Instinct MI325X

VRAM 256GB
FP32 163 TFLOPS
TDP 750W
From $1.69/h 3 providers

📊 Detailed Specifications Comparison

Specification GH200 Instinct MI325X Difference
Architecture & Design
Architecture Hopper + Grace CDNA 3 -
Process Node 4nm 5nm -
Target Market datacenter datacenter -
Form Factor Superchip OAM -
Memory & Bandwidth
VRAM Capacity 96GB 256GB -63%
Memory Type HBM3 HBM3e -
Memory Bandwidth 4.0 TB/s 6.0 TB/s -33%
Memory Bus Width 6144-bit 8192-bit -
Compute Infrastructure
CUDA Cores 16,896 N/A
Tensor Cores (AI) 528 N/A
Stream Processors N/A 19,456
AI & Compute Performance (TFLOPS)
FP32 (Single Precision) 67 TFLOPS 163 TFLOPS -59%
FP16 (Half Precision) 1,979 TFLOPS 2,600 TFLOPS -24%
TF32 (Tensor Float) 989 TFLOPS N/A
FP64 (Double Precision) 34 TFLOPS N/A
Power & Efficiency
TDP (Thermal Design Power) 900W 750W +20%
PCIe Interface PCIe 5.0 x16 PCIe 5.0 x16 -
Multi-GPU Interconnect NVLink-C2C (900 GB/s) None -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

AMD Instinct MI325X

Higher VRAM capacity and memory bandwidth are critical for training large language models. The Instinct MI325X offers 256GB compared to 96GB.

AI Inference

AMD Instinct MI325X

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

NVIDIA GH200 Grace Hopper

Based on current cloud pricing, the GH200 starts at a lower hourly rate.

Automated Comparison

Technical Deep Dive: GH200 vs Instinct MI325X

This head-to-head pits NVIDIA's Hopper + Grace against AMD's CDNA 3. The Instinct MI325X has a significant **160GB VRAM advantage**, which is crucial for training massive datasets or large language models. From a cost perspective, the **GH200** is currently about **12% cheaper** per hour, offering better value for budget-conscious projects.

NVIDIA GH200 Grace Hopper is Best For:

  • CPU+GPU unified computing
  • Large-memory AI workloads
  • Standard GPU deployments

AMD Instinct MI325X is Best For:

  • AI training
  • Large model inference
  • CUDA-only software

Frequently Asked Questions

Which GPU is better for AI training: GH200 or Instinct MI325X?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The GH200 offers 96GB of HBM3 memory with 4.0 TB/s bandwidth, while the Instinct MI325X provides 256GB of HBM3e with 6.0 TB/s bandwidth. For larger models, the Instinct MI325X's higher VRAM capacity gives it an advantage.

What is the price difference between GH200 and Instinct MI325X in the cloud?

Cloud GPU rental prices vary by provider and region. Based on our data, GH200 starts at $1.49/hour while Instinct MI325X starts at $1.69/hour. This represents a 12% price difference.

Can I use Instinct MI325X instead of GH200 for my workload?

It depends on your specific requirements. If your model fits within 256GB of VRAM and you don't need the additional throughput of the GH200, the Instinct MI325X can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the GH200's NVLink support (NVLink-C2C (900 GB/s)) may be essential.

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