NVIDIA H100 SXM VS AMD Instinct MI355X

Choosing between **H100 SXM** and **Instinct MI355X** depends on your specific AI workload requirements. The **Instinct MI355X** leads in both memory capacity and raw compute power, making it a stronger choice for high-end LLM training. Currently, you can rent these GPUs starting from **$0.73/h** and **$2.29/h** respectively across 48 providers.

NVIDIA

H100 SXM

VRAM 80GB
FP32 67 TFLOPS
TDP 700W
From $0.73/h 46 providers
AMD

Instinct MI355X

VRAM 288GB
FP32 210 TFLOPS
TDP 1000W
From $2.29/h 2 providers

📊 Detailed Specifications Comparison

Specification H100 SXM Instinct MI355X Difference
Architecture & Design
Architecture Hopper CDNA 4 -
Process Node 4nm 3nm -
Target Market datacenter datacenter -
Form Factor SXM5 OAM -
Memory & Bandwidth
VRAM Capacity 80GB 288GB -72%
Memory Type HBM3 HBM3e -
Memory Bandwidth 3.35 TB/s 8.0 TB/s -58%
Memory Bus Width 5120-bit 8192-bit -
Compute Infrastructure
CUDA Cores 16,896 N/A
Tensor Cores (AI) 528 N/A
Stream Processors N/A 24,576
AI & Compute Performance (TFLOPS)
FP32 (Single Precision) 67 TFLOPS 210 TFLOPS -68%
FP16 (Half Precision) 1,979 TFLOPS N/A
TF32 (Tensor Float) 989 TFLOPS N/A
FP64 (Double Precision) 34 TFLOPS N/A
INT8 (Integer Precision) 3,958 TOPS N/A
Power & Efficiency
TDP (Thermal Design Power) 700W 1000W -30%
PCIe Interface PCIe 5.0 x16 PCIe 5.0 x16 -
Multi-GPU Interconnect NVLink 4.0 (900 GB/s) None -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

NVIDIA H100 SXM

Higher VRAM capacity and memory bandwidth are critical for training large language models. The Instinct MI355X offers 288GB compared to 80GB.

AI Inference

NVIDIA H100 SXM

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

NVIDIA H100 SXM

Based on current cloud pricing, the H100 SXM starts at a lower hourly rate.

Automated Comparison

Technical Deep Dive: H100 SXM vs Instinct MI355X

This head-to-head pits NVIDIA's Hopper against AMD's CDNA 4. The Instinct MI355X has a significant **208GB VRAM advantage**, which is crucial for training massive datasets or large language models. From a cost perspective, the **H100 SXM** is currently about **68% cheaper** per hour, offering better value for budget-conscious projects.

NVIDIA H100 SXM is Best For:

  • LLM training
  • Foundation model pre-training
  • Small-scale inference

AMD Instinct MI355X is Best For:

  • Massive LLM training
  • Budget projects

Frequently Asked Questions

Which GPU is better for AI training: H100 SXM or Instinct MI355X?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The H100 SXM offers 80GB of HBM3 memory with 3.35 TB/s bandwidth, while the Instinct MI355X provides 288GB of HBM3e with 8.0 TB/s bandwidth. For larger models, the Instinct MI355X's higher VRAM capacity gives it an advantage.

What is the price difference between H100 SXM and Instinct MI355X in the cloud?

Cloud GPU rental prices vary by provider and region. Based on our data, H100 SXM starts at $0.73/hour while Instinct MI355X starts at $2.29/hour. This represents a 68% price difference.

Can I use Instinct MI355X instead of H100 SXM for my workload?

It depends on your specific requirements. If your model fits within 288GB of VRAM and you don't need the additional throughput of the H100 SXM, the Instinct MI355X can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the H100 SXM's NVLink support (NVLink 4.0 (900 GB/s)) may be essential.

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