NVIDIA H200 VS AMD Instinct MI250

Choosing between **H200** and **Instinct MI250** depends on your specific AI workload requirements. The **H200** leads in both memory capacity and raw compute power, making it a stronger choice for high-end LLM training. Currently, you can rent these GPUs starting from **$1.49/h** and **$1.30/h** respectively across 5 providers.

NVIDIA

H200

VRAM 141GB
FP32 67 TFLOPS
TDP 700W
From $1.49/h 4 providers
AMD

Instinct MI250

VRAM 128GB
FP32 45.3 TFLOPS
TDP 500W
From $1.30/h 1 providers

📊 Detailed Specifications Comparison

Specification H200 Instinct MI250 Difference
Architecture & Design
Architecture Hopper CDNA 2 -
Process Node 4nm 6nm -
Target Market datacenter datacenter -
Form Factor SXM5 OAM -
Memory & Bandwidth
VRAM Capacity 141GB 128GB +10%
Memory Type HBM3e HBM2e -
Memory Bandwidth 4.8 TB/s 3.2 TB/s +50%
Memory Bus Width 6144-bit 8192-bit -
Compute Infrastructure
CUDA Cores 16,896 N/A
Tensor Cores (AI) 528 N/A
Stream Processors N/A 13,312
AI & Compute Performance (TFLOPS)
FP32 (Single Precision) 67 TFLOPS 45.3 TFLOPS +48%
FP16 (Half Precision) 1,979 TFLOPS N/A
TF32 (Tensor Float) 989 TFLOPS N/A
FP64 (Double Precision) 34 TFLOPS 45.3 TFLOPS -25%
INT8 (Integer Precision) 3,958 TOPS N/A
Power & Efficiency
TDP (Thermal Design Power) 700W 500W +40%
PCIe Interface PCIe 5.0 x16 PCIe 4.0 x16 -
Multi-GPU Interconnect NVLink 4.0 (900 GB/s) None -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

NVIDIA H200

Higher VRAM capacity and memory bandwidth are critical for training large language models. The H200 offers 141GB compared to 128GB.

AI Inference

NVIDIA H200

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

AMD Instinct MI250

Based on current cloud pricing, the Instinct MI250 starts at a lower hourly rate.

Automated Comparison

Technical Deep Dive: H200 vs Instinct MI250

This head-to-head pits NVIDIA's Hopper against AMD's CDNA 2. The H200 has a significant **13GB VRAM advantage**, which is crucial for training massive datasets or large language models. From a cost perspective, the **Instinct MI250** is currently about **13% cheaper** per hour, offering better value for budget-conscious projects.

NVIDIA H200 is Best For:

  • LLM inference at scale
  • Large context window models
  • Budget deployments

AMD Instinct MI250 is Best For:

  • HPC
  • Matrix math workloads
  • CUDA native apps

Frequently Asked Questions

Which GPU is better for AI training: H200 or Instinct MI250?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The H200 offers 141GB of HBM3e memory with 4.8 TB/s bandwidth, while the Instinct MI250 provides 128GB of HBM2e with 3.2 TB/s bandwidth. For larger models, the H200's higher VRAM capacity gives it an advantage.

What is the price difference between H200 and Instinct MI250 in the cloud?

Cloud GPU rental prices vary by provider and region. Based on our data, H200 starts at $1.49/hour while Instinct MI250 starts at $1.30/hour. This represents a 15% price difference.

Can I use Instinct MI250 instead of H200 for my workload?

It depends on your specific requirements. If your model fits within 128GB of VRAM and you don't need the additional throughput of the H200, the Instinct MI250 can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the H200's NVLink support (NVLink 4.0 (900 GB/s)) may be essential.

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