NVIDIA Tesla K80 VS AMD Instinct MI250

Choosing between **K80** and **Instinct MI250** depends on your specific AI workload requirements. The **Instinct MI250** leads in both memory capacity and raw compute power, making it a stronger choice for high-end LLM training. Currently, you can rent these GPUs starting from **$0.10/h** and **$1.30/h** respectively across 3 providers.

NVIDIA

K80

VRAM 24GB
FP32 8.7 TFLOPS
TDP 300W
From $0.10/h 2 providers
AMD

Instinct MI250

VRAM 128GB
FP32 45.3 TFLOPS
TDP 500W
From $1.30/h 1 providers

📊 Detailed Specifications Comparison

Specification K80 Instinct MI250 Difference
Architecture & Design
Architecture Kepler CDNA 2 -
Process Node 28nm 6nm -
Target Market datacenter datacenter -
Form Factor Dual-slot PCIe OAM -
Memory & Bandwidth
VRAM Capacity 24GB 128GB -81%
Memory Type GDDR5 HBM2e -
Memory Bandwidth 480 GB/s 3.2 TB/s -85%
Memory Bus Width 384-bit 8192-bit -
Compute Infrastructure
CUDA Cores 4,992 N/A
Stream Processors N/A 13,312
AI & Compute Performance (TFLOPS)
FP32 (Single Precision) 8.7 TFLOPS 45.3 TFLOPS -81%
FP64 (Double Precision) N/A 45.3 TFLOPS
Power & Efficiency
TDP (Thermal Design Power) 300W 500W -40%
PCIe Interface PCIe 3.0 x16 PCIe 4.0 x16 -

🎯 Use Case Recommendations

🧠

LLM & Large Model Training

AMD Instinct MI250

Higher VRAM capacity and memory bandwidth are critical for training large language models. The Instinct MI250 offers 128GB compared to 24GB.

AI Inference

AMD Instinct MI250

For inference workloads, performance per watt matters most. Consider the balance between FP16/INT8 throughput and power consumption.

💰

Budget-Conscious Choice

NVIDIA Tesla K80

Based on current cloud pricing, the K80 starts at a lower hourly rate.

Automated Comparison

Technical Deep Dive: K80 vs Instinct MI250

This head-to-head pits NVIDIA's Kepler against AMD's CDNA 2. The Instinct MI250 has a significant **104GB VRAM advantage**, which is crucial for training massive datasets or large language models. From a cost perspective, the **K80** is currently about **92% cheaper** per hour, offering better value for budget-conscious projects.

NVIDIA Tesla K80 is Best For:

  • Old software support
  • Any modern AI

AMD Instinct MI250 is Best For:

  • HPC
  • Matrix math workloads
  • CUDA native apps

Frequently Asked Questions

Which GPU is better for AI training: K80 or Instinct MI250?

For AI training, the key factors are VRAM size, memory bandwidth, and tensor core performance. The K80 offers 24GB of GDDR5 memory with 480 GB/s bandwidth, while the Instinct MI250 provides 128GB of HBM2e with 3.2 TB/s bandwidth. For larger models, the Instinct MI250's higher VRAM capacity gives it an advantage.

What is the price difference between K80 and Instinct MI250 in the cloud?

Cloud GPU rental prices vary by provider and region. Based on our data, K80 starts at $0.10/hour while Instinct MI250 starts at $1.30/hour. This represents a 92% price difference.

Can I use Instinct MI250 instead of K80 for my workload?

It depends on your specific requirements. If your model fits within 128GB of VRAM and you don't need the additional throughput of the K80, the Instinct MI250 can be a cost-effective alternative. However, for workloads requiring maximum memory capacity or multi-GPU scaling, the K80's architecture may be essential.

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